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INSIG1 anticorps (Middle Region)

INSIG1 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN635167
  • Antigène Voir toutes INSIG1 Anticorps
    INSIG1 (Insulin Induced Gene 1 (INSIG1))
    Épitope
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 28
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 28
    Lapin
    Clonalité
    • 28
    Polyclonal
    Conjugué
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    Cet anticorp INSIG1 est non-conjugé
    Application
    • 24
    • 17
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificité
    INSIG1 antibody was raised against the middle region of INSIG1
    Purification
    Affinity purified
    Immunogène
    INSIG1 antibody was raised using the middle region of INSIG1 corresponding to a region with amino acids WWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINH
    Top Product
    Discover our top product INSIG1 Anticorps primaire
  • Indications d'application
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    INSIG1 Blocking Peptide, catalog no. 33R-10042, is also available for use as a blocking control in assays to test for specificity of this INSIG1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INSIG1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    INSIG1 (Insulin Induced Gene 1 (INSIG1))
    Autre désignation
    INSIG1 (INSIG1 Produits)
    Synonymes
    anticorps cl-6, anticorps cl6, anticorps CL-6, anticorps CL6, anticorps fb55a03, anticorps fi35b10, anticorps wu:fb55a03, anticorps wu:fi35b10, anticorps zgc:55439, anticorps 1810013C12Rik, anticorps Insig-1, anticorps INSIG-1, anticorps insulin induced gene 1, anticorps insulin induced gene 1 L homeolog, anticorps INSIG1, anticorps insig1, anticorps insig1.L, anticorps Insig1
    Sujet
    Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
    Poids moléculaire
    25 kDa (MW of target protein)
    Pathways
    ER-Nucleus Signaling
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