EDAR anticorps (Middle Region)
Aperçu rapide pour EDAR anticorps (Middle Region) (ABIN636121)
Antigène
Voir toutes EDAR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- Ectodysplasin A Receptor antibody was raised against the middle region of EDAR
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Purification
- Affinity purified
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Immunogène
- Ectodysplasin A Receptor antibody was raised using the middle region of EDAR corresponding to a region with amino acids PAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGV
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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Ectodysplasin A Receptor Blocking Peptide, (ABIN5613300), is also available for use as a blocking control in assays to test for specificity of this Ectodysplasin A Receptor antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EDAR antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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Autre désignation
- Ectodysplasin A Receptor
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Sujet
- EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
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Poids moléculaire
- 48 kDa (MW of target protein)
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Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
Antigène
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