CLCF1 anticorps
Aperçu rapide pour CLCF1 anticorps (ABIN636624)
Antigène
Voir toutes CLCF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Purification
- Purified
-
Immunogène
- NNT1 antibody was raised in rabbit using highly pure recombinant human NNT-1/BCSF-3 as the immunogen.
-
-
-
-
Indications d'application
- Optimal conditions should be determined byt he investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Concentration
- Lot specific
-
Buffer
- Lyophilized from PBS, pH 7.2.
-
Conseil sur la manipulation
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
-
-
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
-
Autre désignation
- NNT1
-
Sujet
- NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
-
Poids moléculaire
- 22.4 kDa (predicted detection band MW)
-
Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
-