L’anticorps Lapin Polyclonal anti-CD22 a été validé pour WB, ELISA et Inhibition. Il convient pour détecter CD22 dans des échantillons de Humain. Il y a 1 publication disponible.
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Lyophilized
Concentration
Lot specific
Buffer
Lyophilized from PBS, pH 7.2.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
Lennon, Cao, Hall, Vickers, Barker: "The red blood cell as a novel regulator of human B-cell activation." dans: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).
Antigène
CD22
(CD22 Molecule (CD22))
Autre désignation
CD22
Sujet
CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand.