PAI1 anticorps
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- Antigène Voir toutes PAI1 (SERPINE1) Anticorps
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAI1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
- Purification
- Purified
- Immunogène
- PAI1 antibody was raised in rabbit using highly pure recombinant human PAI-1 as the immunogen.
- Top Product
- Discover our top product SERPINE1 Anticorps primaire
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- Indications d'application
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ELISA: 0.5-2 µg/mL, Inhibition: >15 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS, pH 7.2.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Antigène
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Autre désignation
- PAI1 (SERPINE1 Produits)
- Synonymes
- anticorps PAI, anticorps PAI-1, anticorps PAI1, anticorps PLANH1, anticorps SERPINE1, anticorps si:ch211-138a11.1, anticorps Planh1, anticorps PAI1A, anticorps Pai1, anticorps Pai1aa, anticorps Planh, anticorps RATPAI1A, anticorps serpin family E member 1, anticorps serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog, anticorps serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, anticorps serine (or cysteine) peptidase inhibitor, clade E, member 1, anticorps SERPINE1, anticorps serpine1.L, anticorps serpine1, anticorps Serpine1
- Sujet
- Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases.
- Poids moléculaire
- 42.7 kDa (predicted detection band MW)
- Pathways
- Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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