GDNF anticorps
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- Antigène Voir toutes GDNF Anticorps
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GDNF est non-conjugé
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Application
- Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
- Purification
- Purified
- Immunogène
- GDNF antibody was raised in rabbit using highly pure recombinant human GDNF as the immunogen.
- Top Product
- Discover our top product GDNF Anticorps primaire
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- Indications d'application
- Optimal conditions should be determined byt he investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS, pH 7.2.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Antigène
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Autre désignation
- GDNF (GDNF Produits)
- Synonymes
- anticorps gdnf, anticorps GDNF, anticorps AI385739, anticorps gdnfa, anticorps hfb1-gdnf, anticorps ATF1, anticorps ATF2, anticorps HFB1-GDNF, anticorps HSCR3, anticorps glial cell derived neurotrophic factor, anticorps glial cell derived neurotrophic factor a, anticorps glial cell line derived neurotrophic factor, anticorps glial cell derived neurotrophic factor L homeolog, anticorps Gdnf, anticorps gdnfa, anticorps GDNF, anticorps gdnf.L
- Sujet
- GDNF is a disulfide-linked homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFR a(a1-a4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability.
- Pathways
- Signalisation RTK, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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