BDNF anticorps
Aperçu rapide pour BDNF anticorps (ABIN636731)
Antigène
Voir toutes BDNF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- BDNF antibody was raised in rabbit using highly pure recombinant human BDNF as the immunogen.
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Indications d'application
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ELISA: 0.5-2 µg/mL, Inhibition: 0.54-0.81 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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Autre désignation
- BDNF
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Sujet
- BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/tr kb. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues.
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Poids moléculaire
- 27 kDa (predicted detection band MW)
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Pathways
- Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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