BDNF anticorps

N° du produit ABIN636731

Détail du produit anti-BDNF anticorps

Antigène: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BDNF est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogène: BDNF antibody was raised in rabbit using highly pure recombinant human BDNF as the immunogen.

Information d'application

Indications d'application: ELISA: 0.5-2 µg/mL, Inhibition: 0.54-0.81 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur BDNF

Antigène: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Autre désignation: BDNF (BDNF Produits)

Synonymes: anticorps ANON2, anticorps BULN2, anticorps bdnf-A, anticorps BDNF, anticorps bdnf, anticorps brain derived neurotrophic factor, anticorps brain-derived neurotrophic factor, anticorps brain-derived neurotrophic factor L homeolog, anticorps brain-derived neurotrophic factor S homeolog, anticorps BDNF, anticorps Bdnf, anticorps bdnf, anticorps bdnf.L, anticorps bdnf.S

Sujet: BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/tr kb. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues.

Poids moléculaire: 27 kDa (predicted detection band MW)

Pathways: Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity