AGE anticorps
Aperçu rapide pour AGE anticorps (ABIN636761)
Antigène
Voir toutes AGE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Immunogène
- AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.
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Indications d'application
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ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Supplied as liquid whole serum without preservative
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- AGE (Advanced Glycation End Products (AGE))
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Autre désignation
- AGE
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Classe de substances
- Chemical
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Sujet
- Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).
Antigène
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