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PDE8B anticorps

L’anticorps Lapin Polyclonal anti-PDE8B a été validé pour IHC (p). Il convient pour détecter PDE8B dans des échantillons de Humain.
N° du produit ABIN636941

Aperçu rapide pour PDE8B anticorps (ABIN636941)

Antigène

Voir toutes PDE8B Anticorps
PDE8B (phosphodiesterase 8B (PDE8B))

Reactivité

  • 14
  • 11
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 20
Lapin

Clonalité

  • 20
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp PDE8B est non-conjugé

Application

  • 13
  • 10
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Purification

    Affinity chromatography purified

    Immunogène

    PDE8 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
  • Indications d'application

    IHC-P: 10 µg/mL
    Optimal conditions should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    Lot specific

    Buffer

    Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
  • Antigène

    PDE8B (phosphodiesterase 8B (PDE8B))

    Autre désignation

    PDE8B

    Sujet

    Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1-11, PDE4, 7 and 8 selectively degrade cAMP. These enzymes are involved in many signal transduction pathways.

    Pathways

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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