PDE8B anticorps
Aperçu rapide pour PDE8B anticorps (ABIN636941)
Antigène
Voir toutes PDE8B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity chromatography purified
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Immunogène
- PDE8 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Indications d'application
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IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
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- PDE8B (phosphodiesterase 8B (PDE8B))
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Autre désignation
- PDE8B
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Sujet
- Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1-11, PDE4, 7 and 8 selectively degrade cAMP. These enzymes are involved in many signal transduction pathways.
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
Antigène
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