Complement C4d anticorps

N° du produit ABIN639407

L’anticorps anti-Complement C4d Monoclonal Souris est utilisé pour la détection de Complement C4d dans des échantillons de Humain. Il a été validé pour ELISA, IHC (fro) et FACS.

Aperçu rapide pour Complement C4d anticorps (ABIN639407)

Antigène: Complement C4d (C4d) (Complement Component C4d (C4d))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement C4d est non-conjugé

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Détail du produit anti-Complement C4d anticorps

Fonction: Mouse Anti-Human C4d (Neoantigen)

Specificité: DS-MB-02780 recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosous.

Attributs du produit: Blood Coagulation Proteins

Purification: Purified

Immunogène: Purified human C4d

Isotype: IgG1

Information d'application

Indications d'application: Immunohistology - Frozen, ELISA, Flow Cytometry

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Borate buffered saline pH8.2 - 8.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur Complement C4d

Antigène: Complement C4d (C4d) (Complement Component C4d (C4d))

Autre désignation: C4d