TLR7 anticorps

N° du produit ABIN639907

Cet anticorps Souris Monoclonal détecte spécifiquement TLR7 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TLR7 anticorps (ABIN639907)

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TLR7 anticorps

Fonction: Mouse Anti-Human TLR7

Specificité: DS-MB-03427 specifically recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein which belongs to the toll-like receptor (TLR) family, and is predominantly expressed in the spleen, lung and placenta. TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules.

Purification: Purified

Immunogène: Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA (dilution: 1/1000, 1/2000), Western Blotting

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades