TLR7 anticorps
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- Antigène Voir toutes TLR7 Anticorps
- TLR7 (Toll-Like Receptor 7 (TLR7))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR7 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Fonction
- Mouse Anti-Human TLR7
- Specificité
- DS-MB-03427 specifically recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein which belongs to the toll-like receptor (TLR) family, and is predominantly expressed in the spleen, lung and placenta. TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules.
- Purification
- Purified
- Immunogène
- Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.
- Isotype
- IgG1
- Top Product
- Discover our top product TLR7 Anticorps primaire
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- Indications d'application
- ELISA (dilution: 1/1000, 1/2000), Western Blotting
- Restrictions
- For Research Use only
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- Concentration
- IgG concentration 1.0 mg/ml
- Buffer
- Phosphate buffered saline pH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- TLR7 (Toll-Like Receptor 7 (TLR7))
- Autre désignation
- TLR7 (TLR7 Produits)
- Synonymes
- anticorps TLR7-like, anticorps RGD1563357, anticorps toll like receptor 7, anticorps toll-like receptor 7, anticorps TLR7, anticorps Tlr7
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
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