GAPDH anticorps (C-Term)

N° du produit ABIN640717

Cet anticorps Chèvre not_set détecte spécifiquement GAPDH dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GAPDH anticorps (C-Term) (ABIN640717)

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reactivité: Humain

Hôte: Chèvre

Conjugué: Cet anticorp GAPDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GAPDH anticorps

Épitope: C-Term

Specificité: DS-PB-00846 recognizes an epitope within the C-terminal (CT) region of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin. ImmunohistologyThis product requires antigen retrieval using heat treatment prior to staining of paraffin sections. TRIS/EDTA buffer pH9.0 is recommended for this purpose.

Réactivité croisée: Chien

Attributs du produit: Goat Anti-Human GAPDH (C-terminus)

Purification: Purified

Immunogène: Peptide sequence C-HQVVSSDFNSDT corresponding to the C-terminal region of GAPDH (NP_002037.2).

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 0.5 mg/ml

Buffer: TRIS buffered saline pH7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur GAPDH

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Autre désignation: GAPDH