PLVAP anticorps

N° du produit ABIN642822

Cet anticorps anti-PLVAP est un anticorps Rat détectant PLVAP dans FACS et IHC (fro). Adapté pour Souris.

Aperçu rapide pour PLVAP anticorps (ABIN642822)

Antigène: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Reactivité: Souris

Hôte: Rat

Conjugué: Cet anticorp PLVAP est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PLVAP anticorps

Specificité: DS-MB-03957 recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.

Attributs du produit: Rat Anti-Mouse PLVAP

Purification: Purified

Isotype: IgG2a

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur PLVAP

Antigène: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Autre désignation: PLVAP