MCAM anticorps (AA 161-189)

N° du produit ABIN650722

Détail du produit anti-MCAM anticorps

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Épitope: AA 161-189

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCAM est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human MCAM.

Clone: RB20606

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MCAM

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: MCAM (MCAM Produits)

Synonymes: anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Poids moléculaire: 71607

ID gène: 4162

NCBI Accession: NP_006491

UniProt: P43121