ILK anticorps (pSer343)

N° du produit ABIN650820

Cet anticorps anti-ILK est un anticorps Lapin Polyclonal détectant ILK dans DB. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour ILK anticorps (pSer343) (ABIN650820)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Dot Blot (DB)

Clone: RB13896

Détail du produit anti-ILK anticorps

Épitope: pSer343

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ILK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S343 of human ILK.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ILK (ABIN650820)

Brooker, Bond, Peng, Kessler: "β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells." dans: Glia, Vol. 64, Issue 7, pp. 1235-51, (2018) (PubMed).

Srikanth, Das, Berns, Kim, Stupp, Kessler: "Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition." dans: Neuro-oncology, Vol. 15, Issue 3, pp. 319-29, (2013) (PubMed).

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: ILK

Sujet: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Poids moléculaire: 51419

ID gène: 3611

NCBI Accession: NP_001014794, NP_001014795, NP_001265370, NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration