CCR1 anticorps (N-Term)

N° du produit ABIN651052

Cet anticorps Lapin Polyclonal détecte spécifiquement CCR1 dans WB, FACS et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CCR1 anticorps (N-Term) (ABIN651052)

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25939

Détail du produit anti-CCR1 anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR1.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CCR1

Sujet: CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Poids moléculaire: 41173

ID gène: 1230

NCBI Accession: NP_001286

UniProt: P32246