BBS10 anticorps (C-Term)

N° du produit ABIN2840061

L’anticorps anti-BBS10 Polyclonal Lapin est utilisé pour la détection de BBS10 dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour BBS10 anticorps (C-Term) (ABIN2840061)

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB24715

Détail du produit anti-BBS10 anticorps

Épitope: AA 515-544, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BBS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-544 amino acids from the C-terminal region of human BBS10.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur BBS10

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Autre désignation: BBS10

Sujet: BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.

Poids moléculaire: 80838

ID gène: 79738

NCBI Accession: NP_078961

UniProt: Q8TAM1