FOLR2 anticorps (AA 18-46)

N° du produit ABIN651222

Détail du produit anti-FOLR2 anticorps

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Épitope: AA 18-46

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOLR2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids of human FOLR2.

Clone: RB24013

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-FOLR2 (ABIN651222)

Puligujja, McMillan, Kendrick, Li, Balkundi, Smith, Veerubhotla, Edagwa, Kabanov, Bronich, Gendelman, Liu: "Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 9, Issue 8, pp. 1263-73, (2013) (PubMed).

Détails sur FOLR2

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: FOLR2 (FOLR2 Produits)

Synonymes: anticorps FOLR2, anticorps BETA-HFR, anticorps FBP, anticorps FBP/PL-1, anticorps FR-BETA, anticorps FR-P3, anticorps FBP2, anticorps Folbp-2, anticorps Folbp2, anticorps folate receptor 1, anticorps folate receptor beta, anticorps folate receptor 2 (fetal), anticorps FOLR1, anticorps FOLR2, anticorps Folr2

Sujet: FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Poids moléculaire: 29280

ID gène: 2350

NCBI Accession: NP_000794, NP_001107006, NP_001107007, NP_001107008

UniProt: P14207

Pathways: Dicarboxylic Acid Transport