FOLR2 anticorps

N° du produit ABIN2856196

Cet anticorps Lapin Polyclonal détecte spécifiquement FOLR2 dans WB, IHC, IHC (p), IF et ICC. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour FOLR2 anticorps (ABIN2856196)

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOLR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-FOLR2 anticorps

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))
Folate receptor beta antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Folate Receptor beta. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-FOLR2 (ABIN2856196)

Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." dans: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

Détails sur FOLR2

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: folate receptor beta

Sujet: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Secreted

Poids moléculaire: 29 kDa

ID gène: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport