ATF6B anticorps (C-Term)

N° du produit ABIN651294

Cité dans 1 publication. Cet anticorps anti-ATF6B Polyclonal Lapin (Clone RB25603) (ABIN651294) détecte spécifiquement ATF6B dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Hamster.

Aperçu rapide pour ATF6B anticorps (C-Term) (ABIN651294)

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivité: Humain, Souris, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25603

Détail du produit anti-ATF6B anticorps

Épitope: AA 560-589, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ATF6B (ABIN651294)

So, Chen, Wang, Wu, Huang, Lai, Pan, Kang, Huang: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." dans: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: CREBL1

Sujet: CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Poids moléculaire: 76709

ID gène: 1388

NCBI Accession: NP_001129625, NP_004372

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction