ATF6B anticorps

N° du produit ABIN7245755

Détail du produit anti-ATF6B anticorps

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human ATF6B

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: ATF6B (ATF6B Produits)

Synonymes: anticorps CREBL1, anticorps CREB-RP, anticorps G13, anticorps AA617266, anticorps ATF6beta, anticorps Creb-rp, anticorps Crebl1, anticorps activating transcription factor 6 beta, anticorps cyclic AMP-dependent transcription factor ATF-6 beta, anticorps ATF6B, anticorps LOC745411, anticorps Atf6b

Sujet: The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 77 kDa

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction