Cet anticorps Lapin Polyclonal détecte spécifiquement CD63 dans FACS, WB et IHC (p). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CD63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid freeze-thaw cycles.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Date de péremption
6 months
Meng, Müller, Milde-Langosch, Trillsch, Pantel, Schwarzenbach: "Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer." dans: Oncotarget, Vol. 7, Issue 13, pp. 16923-35, (2017) (PubMed).
García-Contreras, Vera-Donoso, Hernández-Andreu, García-Verdugo, Oltra: "Therapeutic potential of human adipose-derived stem cells (ADSCs) from cancer patients: a pilot study." dans: PLoS ONE, Vol. 9, Issue 11, pp. e113288, (2016) (PubMed).
Antigène
CD63
Autre désignation
CD63
Sujet
CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.