TNIP3 anticorps (N-Term)

N° du produit ABIN651787

Cet anticorps Lapin Polyclonal détecte spécifiquement TNIP3 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TNIP3 anticorps (N-Term) (ABIN651787)

Antigène: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB27057

Détail du produit anti-TNIP3 anticorps

Épitope: AA 74-102, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur TNIP3

Antigène: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Autre désignation: TNIP3

Sujet: TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Poids moléculaire: 38943

ID gène: 79931

NCBI Accession: NP_001122315, NP_001231693, NP_079149

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin