TNIP3 anticorps (AA 40-120)

N° du produit ABIN7231850

Cet anticorps Lapin Polyclonal détecte spécifiquement TNIP3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TNIP3 anticorps (AA 40-120) (ABIN7231850)

Antigène: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TNIP3 anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-TNIP3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TNIP3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TNIP3 protein at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TNIP3

Antigène: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Autre désignation: TNIP3

Sujet: TNFAIP3-interacting protein 3, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene proteinTNIP3 (TNFAIP3 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Immune response IL-23 signaling pathway. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Poids moléculaire: 35kD

ID gène: 79931

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin