IFNAR1 anticorps (AA 162-188)

N° du produit ABIN652490

Il existe 1 publication pour ce produit. L’anticorps anti-IFNAR1 Polyclonal Lapin est utilisé pour la détection de IFNAR1 dans des échantillons de Humain. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour IFNAR1 anticorps (AA 162-188) (ABIN652490)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21945

Détail du produit anti-IFNAR1 anticorps

Épitope: AA 162-188

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IFNAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-188 amino acids of human IFNAR1.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-IFNAR1 (ABIN652490)

Dendrou, Cortes, Shipman, Evans, Attfield, Jostins, Barber, Kaur, Kuttikkatte, Leach, Desel, Faergeman, Cheeseman, Neville, Sawcer, Compston, Johnson, Everett, Bell, Karpe, Ultsch, Eigenbrot, McVean et al.: "Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. ..." dans: Science translational medicine, Vol. 8, Issue 363, pp. 363ra149, (2017) (PubMed).

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR1

Sujet: IFNAR1 is the receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha-and beta-subunits themselves.

Poids moléculaire: 63525

ID gène: 3454

NCBI Accession: NP_000620

UniProt: P17181

Pathways: Signalistation JAK/STAT, Hepatitis C