BMI1 anticorps

N° du produit ABIN652702

Cet anticorps Lapin Polyclonal détecte spécifiquement BMI1 dans WB, IF, IHC (p) et FACS. Il présente une réactivité envers Humain et Souris et a été mentionné dans 3+ publications.

Aperçu rapide pour BMI1 anticorps (ABIN652702)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22858

Détail du produit anti-BMI1 anticorps

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BMI1 antibody is generated from rabbits immunized with BMI1 recombinant protein.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:2000. WB: 1:8000. IHC-P: 1:10~50. FC: 1:25. FC: 1:25. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BMI1 (ABIN652702)

Zhou, Dai, Wu, Ji, Karaplis, Goltzman, Yang, Miao: "Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment." dans: Scientific reports, Vol. 6, pp. 29171, (2018) (PubMed).

León-González, Jara-Palacios, Abbas, Heredia, Schini-Kerth: "Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds." dans: Food & function, Vol. 8, Issue 11, pp. 4062-4069, (2018) (PubMed).

Dauleh, Santeramo, Fielding, Ward, Herrmann, Murray, Wilm: "Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0158997, (2017) (PubMed).

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Poids moléculaire: 36949

ID gène: 648

NCBI Accession: NP_001190991, NP_005171

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy