Glutaminase anticorps (C-Term)

N° du produit ABIN652757

Il existe 1 publication pour ce produit. L’anticorps anti-Glutaminase Polyclonal Lapin est utilisé pour la détection de Glutaminase dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF, FACS et IHC (p).

Aperçu rapide pour Glutaminase anticorps (C-Term) (ABIN652757)

Antigène: Glutaminase (GLS)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaminase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB22875

Détail du produit anti-Glutaminase anticorps

Épitope: AA 516-545, C-Term

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human GLS.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IF: 1:25. IF: 1:25. IF: 1:25. WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-Glutaminase (ABIN652757)

Lukey, Greene, Erickson, Wilson, Cerione: "The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy." dans: Nature communications, Vol. 7, pp. 11321, (2016) (PubMed).

Détails sur Glutaminase

Antigène: Glutaminase (GLS)

Autre désignation: GLS

Sujet: Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

Poids moléculaire: 73461

ID gène: 2744

NCBI Accession: NP_001243239, NP_055720

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, L'effet Warburg