ANGPTL4 anticorps (AA 138-167)

N° du produit ABIN653155

Cet anticorps Lapin Polyclonal détecte spécifiquement ANGPTL4 dans WB, FACS et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour ANGPTL4 anticorps (AA 138-167) (ABIN653155)

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGPTL4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18264

Détail du produit anti-ANGPTL4 anticorps

Épitope: AA 138-167

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ANGPTL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human ANGPTL4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ANGPTL4 (ABIN653155)

Huang, Xie, Lin, Li, Huang, Wang, Ye: "The downregulation of ANGPTL4 inhibits the migration and proliferation of tongue squamous cell carcinoma." dans: Archives of oral biology, Vol. 71, pp. 144-149, (2017) (PubMed).

Wan, Wen, Dong, Tang, Liu, Liu, Tao, Gao, Sun, Cao, Fan, Wu: "Establishment of monoclonal HCC cell lines with organ site-specific tropisms." dans: BMC cancer, Vol. 15, pp. 678, (2015) (PubMed).

Détails sur ANGPTL4

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Autre désignation: ANGPTL4

Sujet: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.

Poids moléculaire: 45214

ID gène: 51129

NCBI Accession: NP_001034756, NP_647475

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha