ADRA1B anticorps (AA 270-297)

N° du produit ABIN653353

Cet anticorps Lapin Polyclonal détecte spécifiquement ADRA1B dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour ADRA1B anticorps (AA 270-297) (ABIN653353)

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25170

Détail du produit anti-ADRA1B anticorps

Épitope: AA 270-297

Homologie: B, M, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ADRA1B

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Autre désignation: ADRA1B

Sujet: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Poids moléculaire: 56836

ID gène: 147

NCBI Accession: NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process