SMAD3 anticorps (AA 186-215)

N° du produit ABIN653953

Cet anticorps Lapin Polyclonal détecte spécifiquement SMAD3 dans WB, IF, IHC (p) et FACS. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour SMAD3 anticorps (AA 186-215) (ABIN653953)

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB24758

Détail du produit anti-SMAD3 anticorps

Épitope: AA 186-215

Homologie: C, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from human SMAD3.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SMAD3 (ABIN653953)

Zhou, Liu, Pan, Du, Li, Ma, Yao, Li, Liu: "The let-7g microRNA promotes follicular granulosa cell apoptosis by targeting transforming growth factor-? type 1 receptor." dans: Molecular and cellular endocrinology, Vol. 409, pp. 103-12, (2015) (PubMed).

Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear: "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks." dans: Diabetes, Vol. 62, Issue 8, pp. 2717-27, (2013) (PubMed).

Détails sur SMAD3

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: SMAD3

Sujet: SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Poids moléculaire: 48081

ID gène: 4088

NCBI Accession: NP_001138574, NP_001138575, NP_001138576, NP_005893

UniProt: P84022

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy