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Angiopoietin 2 anticorps (C-Term)

ANGPT2 Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB17789 unconjugated
N° du produit ABIN654062
  • Antigène Voir toutes Angiopoietin 2 (ANGPT2) Anticorps
    Angiopoietin 2 (ANGPT2)
    Épitope
    • 15
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 404-432, C-Term
    Reactivité
    • 75
    • 36
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 77
    • 10
    • 4
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 68
    • 26
    Polyclonal
    Conjugué
    • 48
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiopoietin 2 est non-conjugé
    Application
    • 64
    • 32
    • 32
    • 13
    • 13
    • 11
    • 10
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ANGPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human ANGPT2.
    Clone
    RB17789
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ANGPT2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Alamo, Gallardo, Di Nicolantonio, Pavón, Casanova, Trias, Mangues, Lopez-Pousa, Villaverde, Vázquez, Bardelli, Céspedes, Mangues: "Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 464-76, (2015) (PubMed).

    Alamo, Gallardo, Pavón, Casanova, Trias, Mangues, Vázquez, Villaverde, Mangues, Céspedes: "Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models." dans: Disease models & mechanisms, Vol. 7, Issue 3, pp. 387-96, (2014) (PubMed).

  • Antigène
    Angiopoietin 2 (ANGPT2)
    Autre désignation
    ANGPT2 (ANGPT2 Produits)
    Synonymes
    anticorps AGPT2, anticorps ANG2, anticorps Agpt2, anticorps Ang-2, anticorps Ang2, anticorps ang2, anticorps angpt2, anticorps ANGIOPOIETIN-2, anticorps ANG-2, anticorps ANGPT2, anticorps Angrp, anticorps Rnase5b, anticorps ANG3, anticorps C11orf2, anticorps C11orf3, anticorps FFR, anticorps angiopoietin 2, anticorps angiopoietin 2b, anticorps angiogenin, ribonuclease A family, member 2, anticorps VPS51, GARP complex subunit, anticorps ANGPT2, anticorps Angpt2, anticorps angpt2b, anticorps Ang2, anticorps VPS51
    Sujet
    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
    Poids moléculaire
    56919
    ID gène
    285
    NCBI Accession
    NP_001112359, NP_001112360, NP_001138
    UniProt
    O15123
    Pathways
    Signalisation RTK
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