Ensa anticorps (AA 39-66)
Aperçu rapide pour Ensa anticorps (AA 39-66) (ABIN654413)
Antigène
Voir toutes Ensa (ENSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 39-66
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Homologie
- B, C, Zf, Pig, Rat, X
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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Autre désignation
- ENSA
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Sujet
- ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.
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Poids moléculaire
- 13389
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ID gène
- 2029
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NCBI Accession
- NP_004427, NP_996925, NP_996926, NP_996927, NP_996928, NP_996929, NP_996930, NP_997051
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UniProt
- O43768
Antigène
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