Complement C2 anticorps (N-Term)
Aperçu rapide pour Complement C2 anticorps (N-Term) (ABIN2844317)
Antigène
Voir toutes Complement C2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 147-176, N-Term
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Specificité
- This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2.
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 AA from the N-terminal region of human C2.
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Isotype
- Ig Fraction
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Indications d'application
- WB = 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.26 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Complement C2
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Autre désignation
- C2
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Sujet
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Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Synonyms: Complement C2,C2, -
Poids moléculaire
- 83268 DA
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ID gène
- 717
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NCBI Accession
- NP_000054
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UniProt
- P06681
Antigène
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