Complement Factor H anticorps (AA 751-780)
Aperçu rapide pour Complement Factor H anticorps (AA 751-780) (ABIN654896)
Antigène
Voir toutes Complement Factor H (CFH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 751-780
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.
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Isotype
- IgG
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Indications d'application
- IF: 1:25. IF: 1:25. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Complement Factor H (CFH)
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Autre désignation
- CFH
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Sujet
- This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Poids moléculaire
- 139096
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ID gène
- 3075
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NCBI Accession
- NP_000177
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UniProt
- P08603
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Pathways
- Système du Complément, Cellular Response to Molecule of Bacterial Origin
Antigène
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