TdT anticorps (C-Term)
Aperçu rapide pour TdT anticorps (C-Term) (ABIN655508)
Antigène
Voir toutes TdT (DNTT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 438-467, C-Term
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Homologie
- M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the C-terminal region of human TdT.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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Autre désignation
- TdT
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Sujet
- This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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Poids moléculaire
- 58536
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ID gène
- 1791
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NCBI Accession
- NP_001017520, NP_004079
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UniProt
- P04053
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Pathways
- Réparation de l'ADN
Antigène
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