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PCDHGA8 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-PCDHGA8 a été validé pour WB, IF et IHC (p). Il convient pour détecter PCDHGA8 dans des échantillons de Humain.
N° du produit ABIN655955

Aperçu rapide pour PCDHGA8 anticorps (C-Term) (ABIN655955)

Antigène

Voir toutes PCDHGA8 Anticorps
PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))

Reactivité

Humain

Hôte

  • 9
  • 2
Lapin

Clonalité

  • 10
  • 1
Polyclonal

Conjugué

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PCDHGA8 est non-conjugé

Application

  • 11
  • 9
  • 8
  • 8
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB31662
  • Épitope

    • 7
    • 2
    • 2
    • 1
    • 1
    AA 781-808, C-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This PCDHGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human PCDHGA8.

    Isotype

    Ig Fraction
  • Indications d'application

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))

    Autre désignation

    PCDHGA8

    Sujet

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

    Poids moléculaire

    101480

    ID gène

    9708

    NCBI Accession

    NP_054723, NP_114477

    UniProt

    Q9Y5G5
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