DDR1 anticorps (PE)

N° du produit ABIN6559828

L’anticorps anti-DDR1 Monoclonal Souris est utilisé pour la détection de DDR1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour DDR1 anticorps (PE) (ABIN6559828)

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDR1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 51D6

Détail du produit anti-DDR1 anticorps (PE)

Fonction: Anti-Hu CD167a PE

Réactivité croisée (Details): Human

Attributs du produit: The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: CD167a-transfected NIH-3T3 cells

Isotype: IgM

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze,Protect from prolonged exposure to light

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: CD167a

Sujet: Discoidin domain receptor tyrosine kinase 1,CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling.,EDDR1, MCK10, NTRK4, PTK3A, RTK6, CAK, TRKE, DDR1

ID gène: 780

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration