DDR1 anticorps (PE)
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- Antigène Voir toutes DDR1 Anticorps
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DDR1 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.
- Réactivité croisée (Details)
- Human
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- CD167a-transfected NIH-3T3 cells
- Clone
- 51D6
- Isotype
- IgM
- Top Product
- Discover our top product DDR1 Anticorps primaire
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- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Commentaires
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
- Autre désignation
- CD167a (DDR1 Produits)
- Synonymes
- anticorps CG11573, anticorps CG13984, anticorps CG13985, anticorps CG33531, anticorps CG9488, anticorps CG9490, anticorps CT33540, anticorps DDR, anticorps Dmel\\CG33531, anticorps Dmel_CG13984, anticorps 6030432F18, anticorps AI323681, anticorps CD167a, anticorps Cak, anticorps Nep, anticorps PTK3A, anticorps CAK, anticorps CD167, anticorps EDDR1, anticorps HGK2, anticorps MCK10, anticorps NEP, anticorps NTRK4, anticorps PTK3, anticorps RTK6, anticorps TRKE, anticorps Drd1, anticorps PTK3D, anticorps Discoidin domain receptor, anticorps discoidin domain receptor family, member 1, anticorps discoidin domain receptor tyrosine kinase 1, anticorps Ddr, anticorps Ddr1, anticorps DDR1
- Sujet
- Discoidin domain receptor tyrosine kinase 1,CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling.,EDDR1, MCK10, NTRK4, PTK3A, RTK6, CAK, TRKE, DDR1
- ID gène
- 780
- UniProt
- Q08345
- Pathways
- Signalisation RTK, Smooth Muscle Cell Migration
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