PAK6 anticorps (AA 268-297)
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- Antigène Voir toutes PAK6 Anticorps
- PAK6 (P21-Activated Kinase 6 (PAK6))
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Épitope
- AA 268-297
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This PAK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the Central region of human PAK6.
- Clone
- RB31991
- Isotype
- Ig Fraction
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- Indications d'application
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Autre désignation
- PAK6 (PAK6 Produits)
- Synonymes
- anticorps PAK5, anticorps 4732456M09, anticorps pak6, anticorps si:ch211-158b22.3, anticorps p21 (RAC1) activated kinase 6, anticorps p21 protein (Cdc42/Rac)-activated kinase 6, anticorps p21 protein (Cdc42/Rac)-activated kinase 6b, anticorps PAK6, anticorps Pak6, anticorps pak6b
- Sujet
- This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
- Poids moléculaire
- 74869
- ID gène
- 56924
- NCBI Accession
- NP_001122100, NP_001122101, NP_001263646, NP_001263647, NP_064553
- UniProt
- Q9NQU5
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