TPSAB1 anticorps (C-Term)

N° du produit ABIN656204

L’anticorps Lapin Polyclonal anti-TPSAB1 a été validé pour WB. Il convient pour détecter TPSAB1 dans des échantillons de Souris.

Aperçu rapide pour TPSAB1 anticorps (C-Term) (ABIN656204)

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPSAB1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB19908

Détail du produit anti-TPSAB1 anticorps

Épitope: AA 249-275, C-Term

Homologie: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TPSAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-275 amino acids from the C-terminal region of human TPSAB1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TPSAB1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur TPSAB1

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Autre désignation: TPSAB1

Sujet: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Poids moléculaire: 30515

ID gène: 7177

NCBI Accession: NP_003285

UniProt: Q15661