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PITRM1 anticorps (AA 490-518)

L’anticorps Lapin Polyclonal anti-PITRM1 a été validé pour WB. Il convient pour détecter PITRM1 dans des échantillons de Humain.
N° du produit ABIN656324

Aperçu rapide pour PITRM1 anticorps (AA 490-518) (ABIN656324)

Antigène

Voir toutes PITRM1 Anticorps
PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivité

  • 28
  • 8
  • 7
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 27
  • 3
Lapin

Clonalité

  • 28
  • 2
Polyclonal

Conjugué

  • 25
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PITRM1 est non-conjugé

Application

  • 28
  • 16
  • 12
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB31351
  • Épitope

    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 490-518

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    PITRM1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Date de péremption

    6 months
  • Antigène

    PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

    Autre désignation

    PITRM1

    Sujet

    ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

    Poids moléculaire

    117413

    ID gène

    10531

    NCBI Accession

    NP_001229236, NP_001229238, NP_055704

    UniProt

    Q5JRX3

    Pathways

    Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome
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