PITRM1 anticorps (AA 490-518)

N° du produit ABIN656324

L’anticorps anti-PITRM1 Polyclonal Lapin est utilisé pour la détection de PITRM1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour PITRM1 anticorps (AA 490-518) (ABIN656324)

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITRM1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB31351

Détail du produit anti-PITRM1 anticorps

Épitope: AA 490-518

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PITRM1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur PITRM1

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Autre désignation: PITRM1

Sujet: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Poids moléculaire: 117413

ID gène: 10531

NCBI Accession: NP_001229236, NP_001229238, NP_055704

UniProt: Q5JRX3

Pathways: Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome