PC (AA 53-82), (N-Term) anticorps

N° du produit ABIN656425

Détail du produit

Antigène: PC

Épitope: AA 53-82, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC.

Homologie: Cow (Bovine),Rat (Rattus)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 AA from the N-terminal region of human PC.

Clone: RB31105

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: PC Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: PC

Sujet: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
Synonyms: Pyruvate carboxylase, mitochondrial,PC,

Poids moléculaire: 129634 DA

ID gène: 5091

NCBI Accession: NP_000911, NP_001035806, NP_071504

UniProt: P11498