Cholesterol Esterase anticorps (AA 454-482)
Aperçu rapide pour Cholesterol Esterase anticorps (AA 454-482) (ABIN656486)
Antigène
Voir toutes Cholesterol Esterase (CEL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 454-482
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This CEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the Central region of human CEL.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- Cholesterol Esterase (CEL)
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Autre désignation
- CEL
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Sujet
- The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
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Poids moléculaire
- 79322
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UniProt
- P19835
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Pathways
- Lipid Metabolism
Antigène
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