Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human CYP2S1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Yang, Zhou, Li, Tong, Sun, Qing, Sun, Yang, Hu, Jiang, Yan, He, Wan: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." dans: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).
Yang, Li, Li, Tong, Hu, Yang, Yan, He, Wan: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." dans: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).
Antigène
CYP2S1
(Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))
anticorps 1200011C15Rik, anticorps AU041727, anticorps C79779, anticorps cytochrome P450, family 2, subfamily s, polypeptide 1, anticorps cytochrome P450 family 2 subfamily S member 1, anticorps Cyp2s1, anticorps CYP2S1
Sujet
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.