PSME3 anticorps

N° du produit ABIN6566551

Cet anticorps Lapin Polyclonal détecte spécifiquement PSME3 dans WB et IF. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour PSME3 anticorps (ABIN6566551)

Antigène: PSME3

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PSME3 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human PSME3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IF 1:20 - 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSME3

Antigène: PSME3

Autre désignation: PSME3

Sujet:

Synonyms: 11S regulator complex gamma subunit,11S regulator complex subunit gamma,Activator of multicatalytic protease subunit 3,Ki,Ki antigen,Ki nuclear autoantigen,Ki,PA28 gamma,PA28 gamma,PA28g,PA28gamma,Proteasome (prosome,macropain) activator subunit 3 (PA28 gamma,Ki),Proteasome (prosome,macropain) activator subunit 3,Proteasome activator 28 gamma,Proteasome activator 28 subunit gamma,Proteasome activator complex subunit 3,Proteasome activator subunit 3,PSME3,PSME3,REG GAMMA,REG-gamma

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 32kDa

Calculated_MW: 29kDa/30kDa

ID gène: 10197

UniProt: P61289

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA