CARD8 anticorps

N° du produit ABIN6566566

L’anticorps Lapin Polyclonal anti-CARD8 a été validé pour WB. Il convient pour détecter CARD8 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CARD8 anticorps (ABIN6566566)

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CARD8 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human CARD8

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CARD8

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Autre désignation: CARD8

Sujet:

Synonyms: Apoptotic protein NDPP 1,Apoptotic protein NDPP1,CARD 8,CARD inhibitor of NF kappa B activating ligand,CARD inhibitor of NF kappaB activating ligand,CARD inhibitor of NF kappaB activating ligands,CARD-inhibitor of NF-kappa-B-activating ligand,CARD8,CARD8,CARDINAL,Caspase recruitment domain containing protein 8,Caspase recruitment domain family member 8,Caspase recruitment domain protein 8,Caspase recruitment domain-containing protein 8,DACAR,Dakar,DKFZp779L0366,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP 1,NDPP,NDPP1,TUCAN,Tumor up regulated CARD containing antagonist of CASP9,Tumor up regulated CARD containing antagonist of caspase 9,Tumor up-regulated CARD-containing antagonist of CASP9,tumor up-regulated CARD-containing antagonist of caspase nine,Tumor upregulated CARD containing antagonist of CASP9

Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 32kDa/44kDa/48kDa/55kDa/60kDa

ID gène: 22900

UniProt: Q9Y2G2

Pathways: Positive Regulation of Endopeptidase Activity