NUMA1 anticorps

N° du produit ABIN6566605

Cet anticorps Lapin Polyclonal détecte spécifiquement NUMA1 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NUMA1 anticorps (ABIN6566605)

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NUMA1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human NUMA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:1000 IHC 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NUMA1

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Autre désignation: NUMA1

Sujet:

Synonyms: Centrophilin stabilizes mitotic spindle in mitotic cells,NMP 22,Nuclear matrix protein 22,Nuclear mitotic apparatus protein 1,Nuclear mitotic apparatus protein,NUMA 1,NUMA,NuMA protein,NUMA1,NUMA1,SP H antigen,SP-H antigen,Structural nuclear protein

Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 238kDa

Calculated_MW: 109kDa/200kDa/201kDa/236kDa/238kDa

ID gène: 4926

UniProt: Q14980

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase