Desmocollin 1 anticorps

N° du produit ABIN6566762

Détail du produit anti-Desmocollin 1 anticorps

Antigène: Desmocollin 1 (DSC1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human DSC1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Desmocollin 1

Antigène: Desmocollin 1 (DSC1)

Autre désignation: DSC1 (DSC1 Produits)

Synonymes: anticorps DSC1, anticorps CDHF1, anticorps DG2/DG3, anticorps DSC1b, anticorps DG2DG3, anticorps dg3, anticorps Dsc1a, anticorps Dsc1b, anticorps desmocollin 1, anticorps DSC1, anticorps Dsc1

Sujet:

Synonyms: Cadherin family member 1,CDHF1,Desmocollin1,Desmosomal glycoprotein 2/3,DG2/DG3,DSC 1,DSC1

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.

Poids moléculaire:

Observed_MW: 105kDa

Calculated_MW: 93kDa/99kDa

ID gène: 1823

UniProt: Q08554